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Article

Phenotype-Guided Natural Products Discovery Using Cytological Profiling.

Journal of natural products - 25 Sept 2015

Ochoa Jessica L, Bray Walter M, Lokey R Scott, Linington Roger G

Abstract excerpt

Phenotype-guided natural products discovery is emerging as a useful new discovery tool that addresses challenges in early, unbiased natural product biological annotation. These high-content approaches yield screening results that report directly on the impact of test compounds on cellular processes in target organisms and can be used to predict the modes of action of bioactive constituents from primary screening...

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Identifiers

PMID: 26292657
DOI: 10.1021/acs.jnatprod.5b00455
PMCID: PMC7505087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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