Article
Pharmacological screening of bryophyte extracts that inhibit growth and induce abnormal phenotypes in human HeLa cancer cells.
Fundamental & clinical pharmacology - 1 Aug 2009
Krzaczkowski Lucie, Wright Michel, Rebérioux Delphine, Massiot Georges, Etiévant Chantal, Gairin Jean Edouard
Abstract excerpt
Antitumor activities of substances from natural sources apart from vascular plants and micro-organisms have been poorly investigated. Here we report on a pharmacological screening of a bryophyte extract library using a phenotypic cell-based assay revealing microtubules, centrosomes and DNA. Among the 219 moss extracts tested, we identified 41 extracts acting on cell division with various combinations of...
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