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Article

CCND2, CTNNB1, DDX3X, GLI2, SMARCA4, MYC, MYCN, PTCH1, TP53, and MLL2 gene variants and risk of childhood medulloblastoma.

Journal of neuro-oncology - 1 Oct 2015

Dahlin Anna M, Hollegaard Mads V, Wibom Carl, Andersson Ulrika, Hougaard David M, Deltour Isabelle, Hjalmars Ulf, Melin Beatrice

Abstract excerpt

Recent studies have described a number of genes that are frequently altered in medulloblastoma tumors and that have putative key roles in the development of the disease. We hypothesized that common germline genetic variations in these genes may be associated with medulloblastoma development. Based on recent publications, we selected 10 genes that were frequently altered in medulloblastoma: CCND2, CTNNB1, DDX3X,...

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Identifiers

PMID: 26290144
DOI: 10.1007/s11060-015-1891-1
PMCID: PMC4592490

Genes

CCND2
GLI2
PTCH1
CTNNB1
MYC
MYCN
SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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