Article
LncRNA CDKN2BAS rs2157719 genetic variant contributes to medulloblastoma predisposition.
The journal of gene medicine - 1 Jan 2018
Chen Yi-Dong, Zhang Nasha, Qiu Xiao-Guang, Yuan Jupeng, Yang Ming
Abstract excerpt
BACKGROUND: How germline single nucleotide polymorphisms are involved in the etiology of medulloblastoma remans poorly understood. We hypothesized that CCDKN2A/B rs1063192 and rs4977756 and also the long noncoding RNA (lncRNA) CDKN2BAS rs2157719 glioma susceptibility polymorphisms identified by genome-wide association studies may contribute to medulloblastoma predisposition. METHODS: To test this hypothesis, we...
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