Article
Computational Methods to Target Protein-Protein Interactions.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024
Jastrzębski Michał K
Abstract excerpt
The chapter emphasizes the importance of understanding protein-protein interactions in cellular mechanisms and highlights the role of computational modeling in predicting these interactions. It discusses sequence-based approaches such as evolutionary trace (ET), correlated mutation analysis (CMA), and subtractive correlated mutation (SCM) for identifying crucial amino acid residues, considering interface...
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