Article
A Single Amino Acid Replacement in the Sensor Kinase LiaS Contributes to a Carrier Phenotype in Group A Streptococcus.
Infection and immunity - 1 Nov 2015
Flores Anthony R, Jewell Brittany E, Yelamanchili Dedipya, Olsen Randall J, Musser James M
Abstract excerpt
Despite the high frequency of asymptomatic carriage of bacterial pathogens, we understand little about the bacterial molecular genetic underpinnings of this phenomenon. To obtain new information about the molecular genetic mechanisms underlying carriage of group A Streptococcus (GAS), we performed whole-genome sequencing of GAS strains recovered from a single individual during acute pharyngitis and subsequent...
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