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Article

Natural variant of collagen-like protein a in serotype M3 group a Streptococcus increases adherence and decreases invasive potential.

Infection and immunity - 1 Mar 2015

Flores Anthony R, Jewell Brittany E, Versalovic Erika M, Olsen Randall J, Bachert Beth A, Lukomski Slawomir, Musser James M

Abstract excerpt

Group A Streptococcus (GAS) predominantly exists as a colonizer of the human oropharynx that occasionally breaches epithelial barriers to cause invasive diseases. Despite the frequency of GAS carriage, few investigations into the contributory molecular mechanisms exist. To this end, we identified a naturally occurring polymorphism in the gene encoding the streptococcal collagen-like protein A (SclA) in GAS...

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Identifiers

PMID: 25561712
DOI: 10.1128/IAI.02860-14
PMCID: PMC4333440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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