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Article

Regulatory gene mutation: a driving force behind group a Streptococcus strain- and serotype-specific variation.

Molecular microbiology - 1 Feb 2017

Sarkar Poulomee, Sumby Paul

Abstract excerpt

Data from multiple bacterial pathogens are consistent with regulator-encoding genes having higher mutation frequencies than the genome average. Such mutations drive both strain- and type- (e.g., serotype, haplotype) specific phenotypic heterogeneity, and may challenge public health due to the potential of variants to circumvent established treatment and/or preventative regimes. Here, using the human bacterial...

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Share to Gene Expression Regulation, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27868255
DOI: 10.1111/mmi.13584
PMCID: PMC5296365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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