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Article

β-Lactoglobulin mutant Lys69Asn has attenuated IgE and increased retinol binding activity.

Journal of biotechnology - 20 Oct 2015

Taheri-Kafrani Asghar, Tavakkoli Koupaie Neda, Haertlé Thomas

Abstract excerpt

β-Lactoglobulin (β-LG) is a member of lipocalin superfamily of transporters for small hydrophobic molecules such as retinoids, fatty acids, drugs, and vitamins. β-LG also is one of the major allergens in milk. Despite a lot of research on decreasing cow's milk allergenicity, the effects of mutations of β-LG on recognition by IgE from cow's milk allergy (CMA) patients have not been investigated. We describe here...

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PMID: 26281976
DOI: 10.1016/j.jbiotec.2015.08.006

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