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Article

Characterization of mutants of a highly cross-reactive calcium-binding protein from Brassica pollen for allergen-specific immunotherapy.

Immunobiology - 1 Sept 2013

Garmatiuk Tetiana, Swoboda Ines, Twardosz-Kropfmüller Anna, Dall'Antonia Fabio, Keller Walter, Singh Mohan B, Bhalla Prem L, Okada Takashi, Toriyama Kinya, Weber Milena, Ghannadan Minoo, Sperr Wolfgang R, Blatt Katharina, Valent Peter, Klein Brigitte, Niederberger Verena, Curin Mirela, Balic Nadja, Spitzauer Susanne, Valenta Rudolf

Abstract excerpt

The major turnip (Brassica rapa) pollen allergen, belongs to a family of calcium-binding proteins (i.e., two EF-hand proteins), which occur as highly cross-reactive allergens in pollen of weeds, grasses and trees. In this study, the IgE binding capacity and allergenic activity of three recombinant allergen variants containing mutations in their calcium-binding sites were analyzed in sensitized patients with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23790497
DOI: 10.1016/j.imbio.2013.04.006
PMCID: PMC4573526

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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