Article

Critical structural elements for the antigenicity of wheat allergen LTP1 (Tri a 14) revealed by site-directed mutagenesis

2022-03-16

Abstract excerpt

Lipid transfer proteins (LTPs) were identified as allergens in a large variety of pollens and foods, including cereals. LTPs belong to the prolamin superfamily and display an α-helical fold, with a bundle of four α-helices held together by four disulfide bonds. Wheat LTP1 is involved in allergic reactions to food such as anaphylaxis and wheat-dependent exercise-induced anaphylaxis. To identify critical structural...

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Literature Corpus work: d31d4261-1323-5d4b-9a20-72c517886745
DOI: 10.21203/rs.3.rs-1391837/v1

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