The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye.

doi:10.1167/iovs.14-16020

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye.

Investigative ophthalmology & visual science - 1 Aug 2015

Miyake Masahiro, Yamashiro Kenji, Tamura Hiroshi, Kumagai Kyoko, Saito Masaaki, Sugahara-Kuroda Masako, Yoshikawa Munemitsu, Oishi Maho, Akagi-Kurashige Yumiko, Nakata Isao, Nakanishi Hideo, Gotoh Norimoto, Oishi Akio, Matsuda Fumihiko, Yamada Ryo, Khor Chiea-Chuen, Kurimoto Yasuo, Sekiryu Tetsuju, Tsujikawa Akitaka, Yoshimura Nagahisa

Abstract excerpt

PURPOSE: To correlate a genetic risk score based on age-related macular degeneration (AMD) susceptibility genes with the risk of AMD in the second eye. METHODS: This is a retrospective, open cohort study consisting of 891 unilateral AMD patients, who were followed for at least 12 months and recruited from three institutes. DNAs were genotyped using Illumina OmniExpress, HumanOmni2.5-8, and/or HumanExome. Survival...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forecasting

Share to Genotyping Techniques

Share to Incidence

Share to Macular Degeneration

Share to Receptors, TNF-Related Apoptosis-Inducing Ligand

Share to RNA

Share to Vascular Endothelial Growth Factor A

Source

Open in PubMed

Identifiers

PMID: 26275133
DOI: 10.1167/iovs.14-16020

Genes

ARMS2
CFH
CFI
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye.PMID 26275133Read ↗

The contribution of genetic factors to phenotype and progression of drusen in early age-related macular degeneration.Semantic proximity Read ↗

Susceptibility genes and progression in age-related maculopathy: a study of single eyes.Semantic proximity Read ↗

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced diseaseSemantic proximity Read ↗

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease.Semantic proximity Read ↗

Genome-Wide Meta-analysis Identifies Risk Loci and Improves Disease Prediction of Age-Related Macular Degeneration.Semantic proximity Read ↗

Genetic susceptibility to age-related macular degeneration: a paradigm for dissecting complex disease traits.Semantic proximity Read ↗

Modelling the genetic risk in age-related macular degeneration.Semantic proximity Read ↗

Genetics of Unilateral and Bilateral Age-Related Macular Degeneration Severity Stages.Semantic proximity Read ↗

Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study.Semantic proximity Read ↗

Bivariate Analysis of Age-Related Macular Degeneration Progression Using Genetic Risk Scores.Semantic proximity Read ↗

Genome-wide analysis of disease progression in age-related macular degeneration.Semantic proximity Read ↗

Progression of Age-Related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5) or Chromosome 10 (ARMS2/HTRA1) or Both.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.