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Article

Modelling the genetic risk in age-related macular degeneration.

PloS one - 1 Jan 2012

Grassmann Felix, Fritsche Lars G, Keilhauer Claudia N, Heid Iris M, Weber Bernhard H F

Abstract excerpt

Late-stage age-related macular degeneration (AMD) is a common sight-threatening disease of the central retina affecting approximately 1 in 30 Caucasians. Besides age and smoking, genetic variants from several gene loci have reproducibly been associated with this condition and likely explain a large proportion of disease. Here, we developed a genetic risk score (GRS) for AMD based on 13 risk variants from eight...

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Identifiers

PMID: 22666427
DOI: 10.1371/journal.pone.0037979
PMCID: PMC3364197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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