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Article

Genome-wide analysis of disease progression in age-related macular degeneration.

Human molecular genetics - 1 Mar 2018

Yan Qi, Ding Ying, Liu Yi, Sun Tao, Fritsche Lars G, Clemons Traci, Ratnapriya Rinki, Klein Michael L, Cook Richard J, Liu Yu, Fan Ruzong, Wei Lai, Abecasis Gonçalo R, Swaroop Anand, Chew Emily Y, Weeks Daniel E, Chen Wei

Abstract excerpt

Family- and population-based genetic studies have successfully identified multiple disease-susceptibility loci for Age-related macular degeneration (AMD), one of the first batch and most successful examples of genome-wide association study. However, most genetic studies to date have focused on case-control studies of late AMD (choroidal neovascularization or geographic atrophy). The genetic influences on disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29346644
DOI: 10.1093/hmg/ddy002
PMCID: PMC6059197

Genes

ARMS2
ATF7IP2
C2
C3
CFB
CFH
CTRB1
CTRB2
HTRA1
LIPC
MMP9
TNR

Provenance

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