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Article

Bivariate Analysis of Age-Related Macular Degeneration Progression Using Genetic Risk Scores.

Genetics - 1 May 2017

Ding Ying, Liu Yi, Yan Qi, Fritsche Lars G, Cook Richard J, Clemons Traci, Ratnapriya Rinki, Klein Michael L, Abecasis Gonçalo R, Swaroop Anand, Chew Emily Y, Weeks Daniel E, Chen Wei

Abstract excerpt

Age-related macular degeneration (AMD) is a leading cause of blindness in the developed world. While many AMD susceptibility variants have been identified, their influence on AMD progression has not been elucidated. Using data from two large clinical trials, Age-Related Eye Disease Study (AREDS) and AREDS2, we evaluated the effects of 34 known risk variants on disease progression. In doing so, we calculated the...

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Identifiers

PMID: 28341650
DOI: 10.1534/genetics.116.196998
PMCID: PMC5419464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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