Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study.

JAMA ophthalmology - 1 Mar 2013

Klein Ronald, Myers Chelsea E, Meuer Stacy M, Gangnon Ronald E, Sivakumaran Theru A, Iyengar Sudha K, Lee Kristine E, Klein Barbara E K

Abstract excerpt

OBJECTIVE: To describe the relationships of risk alleles in complement factor H (CFH, rs1061170) and age-related maculopathy susceptibility 2 (ARMS2, rs10490924) to the incidence and progression of age-related macular degeneration (AMD) during a 20-year period. METHODS: There were 4282 persons aged 43 to 86 years at the baseline examination in 1988-1990 enrolled in a population-based cohort study who participated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over
Share to Complement Factor H
Share to Disease Progression
Share to Incidence
Share to Macular Degeneration
Share to Proteins
Share to Risk Assessment
Share to Wisconsin

Source

Open in PubMed Open full text

Identifiers

PMID: 23494043
DOI: 10.1001/jamaophthalmol.2013.713
PMCID: PMC3602927

Genes

ARMS2
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study.PMID 23494043Read ↗

Susceptibility genes and progression in age-related maculopathy: a study of single eyes.Semantic proximity Read ↗

Cigarette smoking and the natural history of age-related macular degeneration: the Beaver Dam Eye Study.Semantic proximity Read ↗

Effect of the Y402H variant in the complement factor H gene on the incidence and progression of age-related macular degeneration: results from multistate models applied to the Beaver Dam Eye Study.Semantic proximity Read ↗

ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study.Semantic proximity Read ↗

The Incidence and Progression of Age-Related Macular Degeneration over 15 Years: The Blue Mountains Eye Study.Semantic proximity Read ↗

Variations in five genes and the severity of age-related macular degeneration: results from the Muenster aging and retina study.Semantic proximity Read ↗

Progression of Age-Related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5) or Chromosome 10 (ARMS2/HTRA1) or Both.Semantic proximity Read ↗

Genetic susceptibility to age-related macular degeneration: a paradigm for dissecting complex disease traits.Semantic proximity Read ↗

Rare and Common Genetic Variants, Smoking, and Body Mass Index: Progression and Earlier Age of Developing Advanced Age-Related Macular Degeneration.Semantic proximity Read ↗

Susceptibility to advanced age-related macular degeneration and alleles of complement factor H, complement factor B, complement component 2, complement component 3, and age-related maculopathy susceptibility 2 genes in a Mexican population.Semantic proximity Read ↗

Genome-Wide Meta-analysis Identifies Risk Loci and Improves Disease Prediction of Age-Related Macular Degeneration.Semantic proximity Read ↗

CFH haplotypes and ARMS2, C2, C3, and CFB alleles show association with susceptibility to age-related macular degeneration in Mexicans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.