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Article

Bcl2 inhibition of mitochondrial DNA repair.

BMC cancer - 13 Aug 2015

Xie Maohua, Doetsch Paul W, Deng Xingming

Abstract excerpt

BACKGROUND: Accumulation of mitochondrial DNA (mtDNA) damage could enhance the frequency of mitochondrial mutations and promote a variety of mitochondria-related diseases, including cancer. However, the mechanism(s) involved are not fully understood. METHODS: Quantitative extended length PCR was used to compare mtDNA and nDNA damage in human lung H1299 cells expressing WT Bcl2 or vector-only control. mtAPE1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to DNA-(Apurinic or Apyrimidinic Site) Lyase

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Source

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Identifiers

PMID: 26268226
DOI: 10.1186/s12885-015-1594-1
PMCID: PMC4535531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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