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Article

The Hepatitis C Virus NS2 Protein Is an Inhibitor of CIDE-B-induced Apoptosis

1 May 2003

Abstract excerpt

Chronic hepatitis C virus (HCV) infection frequently leads to liver cancer. To determine the viral factor(s) potentially involved in viral persistence, we focused our work on NS2, a viral protein of unknown function. To assign a role for NS2, we searched for cellular proteins that interact with NS2. Performing a two-hybrid screen on a human liver cDNA library, we found that NS2 interacted with the liver-specific...

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PMID: 12595532
DOI: 10.1074/jbc.m209732200

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