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Article

Regulation of apoptosis by Bcl-2 cysteine oxidation in human lung epithelial cells.

Molecular biology of the cell - 1 Mar 2013

Luanpitpong Sudjit, Chanvorachote Pithi, Stehlik Christian, Tse William, Callery Patrick S, Wang Liying, Rojanasakul Yon

Abstract excerpt

Hydrogen peroxide is a key mediator of oxidative stress known to be important in various cellular processes, including apoptosis. B-cell lymphoma-2 (Bcl-2) is an oxidative stress-responsive protein and a key regulator of apoptosis; however, the underlying mechanisms of oxidative regulation of Bcl-2 are not well understood. The present study investigates the direct effect of H2O2 on Bcl-2 cysteine oxidation as a...

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Identifiers

PMID: 23363601
DOI: 10.1091/mbc.E12-10-0747
PMCID: PMC3596255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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