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Article

Comparison of Glomerular and Podocyte mRNA Profiles in Streptozotocin-Induced Diabetes

11 Aug 2015

Abstract excerpt

Evaluating the mRNA profile of podocytes in the diabetic kidney may indicate genes involved in the pathogenesis of diabetic nephropathy. To determine if the podocyte-specific gene information contained in mRNA profiles of the whole glomerulus of the diabetic kidney accurately reflects gene expression in the isolated podocytes, we crossed Nos3(-/-) IRG mice with podocin-rtTA and TetON-Cre mice for enhanced green...

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Share to Chronic Kidney Disease and Diabetes
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PMID: 26264855
DOI: 10.1681/asn.2015040421

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