Article
Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti-proteinuric therapies.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jul 2002
Kelly Darren J, Aaltonen Petri, Cox Alison J, Rumble Jon R, Langham Robyn, Panagiotopoulos Sianna, Jerums George, Holthöfer Harry, Gilbert Richard E
Abstract excerpt
BACKGROUND: Mutations in the gene coding for the podocyte slit-pore membrane protein, nephrin, are responsible for the Finnish-type congenital nephrotic syndrome. The present study sought to examine whether nephrin expression may also be altered in experimental diabetes, and how such changes related to the development of proteinuria. In addition, the study also sought to examine nephrin expression in animals...
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