Back to search

Article

Klotho Deficiency Aggravated Diabetes-induced Podocyte injury

2020-02-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Diabetic nephropathy (DN) is a progressive disease, the main pathogeny of which is podocyte injury inducing glomerular filtration barrier and proteinuria. The occurrence and development of DN could be partly attributed to the reactive oxygen species (ROS) generated by mitochondria. However, researches on how mitochondrial dysfunction (MtD) ultimately causes DNA...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d4d4f134-8316-5da1-8da5-dfdcd828143e
DOI
10.21203/rs.2.24085/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Klotho Deficiency Aggravated Diabetes-induced Podocyte injuryDOI 10.21203/rs.2.24085/v1
Impact of klotho on the expression of SRGAP2a in podocytes in diabetic nephropathySemantic proximity
Mitochondrial dysfunction has a central role in diabetic kidney diseaseSemantic proximity
Glomerular Endothelial Mitochondrial Dysfunction Is Essential and Characteristic of Diabetic Kidney Disease SusceptibilitySemantic proximity
NQO1 Alleviates Renal Fibrosis by Inhibiting TLR4/NF-κB and TGF-β/Smad Signaling Pathway in Diabetic NephropathySemantic proximity
Research progress on ferroptosis in diabetic kidney diseaseSemantic proximity
Research Progress on Mitochondrial Dysfunction in Diabetic RetinopathySemantic proximity
Mitochondria: A Novel Therapeutic Target in Diabetic NephropathySemantic proximity
Epigenetics and endoplasmic reticulum in podocytopathy during diabetic nephropathy progressionSemantic proximity
Advances in Murine Models of Diabetic NephropathySemantic proximity
Role of nuclear receptors, lipid metabolism, and mitochondrial function in the pathogenesis of diabetic kidney diseaseSemantic proximity
Model-Dependent Renal Phenotypes in Diabetic Kidney Disease: Comparative Histopathological Characterization of Commonly Used Animal ModelsSemantic proximity
New Insights into Podocyte Biology in Glomerular Health and DiseaseSemantic proximity
Select a neighboring publication to make it the new centre.