Article
Pharmacogenetic Study of Serotonin Transporter and 5HT2A Genotypes in Autism.
Journal of child and adolescent psychopharmacology - 1 Aug 2015
Najjar Fedra, Owley Thomas, Mosconi Matthew W, Jacob Suma, Hur Kwan, Guter Stephen J, Sweeney John A, Gibbons Robert D, Cook Edwin H, Bishop Jeffrey R
Abstract excerpt
OBJECTIVE: The purpose of this study was to determine whether polymorphisms in the serotonin transporter (SLC6A4) and serotonin-2A receptor (HTR2A) genes are associated with response to escitalopram in patients with autism spectrum disorder (ASD). METHODS: Forty-four participants with ASD were enrolled in a 6 week, forced titration, open label examination of the selective serotonin reuptake inhibitor (SSRI)...
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