Article
Association of BDNF, HTR2A, TPH1, SLC6A4, and COMT polymorphisms with tDCS and escitalopram efficacy: ancillary analysis of a double-blind, placebo-controlled trial.
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Apr 2020
Brunoni Andre R, Carracedo Angel, Amigo Olalla M, Pellicer Ana L, Talib Leda, Carvalho Andre F, Lotufo Paulo A, Benseñor Isabela M, Gattaz Wagner, Cappi Carolina
Abstract excerpt
OBJECTIVE: We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, ), and the catechol-O-methyltransferase...