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Article

Lack of evidence for association of the serotonin transporter gene SLC6A4 with autism.

Biological psychiatry - 15 Jul 2006

Ramoz Nicolas, Reichert Jennifer G, Corwin Thomas E, Smith Christopher J, Silverman Jeremy M, Hollander Eric, Buxbaum Joseph D

Abstract excerpt

BACKGROUND: The serotonin transporter (5-HTT) has long been considered likely to play a role in autism. Hyperserotonemia has been consistently found in a proportion of autistic patients, and the use of selective serotonin reuptake inhibitors (SSRIs) can have a positive effect in treating some symptoms of autism. Specific variants of the 5-HTT gene, SLC6A4, especially the insertion-deletion 5-HTTLPR promoter...

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Source

Identifiers

PMID: 16616719
DOI: 10.1016/j.biopsych.2006.01.009

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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