Article
5-HTTLPR Genotype-Specific Phenotype in Children and Adolescents With Autism.
The American journal of psychiatry - 1 Dec 2006
Brune Camille W, Kim Soo-Jeong, Salt Jeff, Leventhal Bennett L, Lord Catherine, Cook Edwin H
Abstract excerpt
OBJECTIVE: The serotonin transporter gene (SLC6A4) is a strong autism candidate gene because of its association with anxiety, aggression and attention, and the effectiveness of selective serotonin reuptake inhibitors (SSRIs) in treating certain behavioral symptoms. In families with individuals wi...
Topics
- Adolescent
- Adult
- Age Factors
- Autistic Disorder
- Child
- Child, Preschool
- Genetic Heterogeneity
- Genotype
- Humans
- Interpersonal Relations
- Introns
- Nonverbal Communication
- Phenotype
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Psychiatric Status Rating Scales
- Serotonin Plasma Membrane Transport Proteins
- Severity of Illness Index