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Article

Variants of the serotonin transporter gene (SLC6A4) significantly contribute to hyperserotonemia in autism.

Molecular psychiatry - 1 Mar 2004

Coutinho A M, Oliveira G, Morgadinho T, Fesel C, Macedo T R, Bento C, Marques C, Ataíde A, Miguel T, Borges L, Vicente A M

Abstract excerpt

The role of the serotonin system in the etiology and pathogenesis of autism spectrum disorders (ASD) is not clearly defined. High levels of platelet serotonin (5-HT) have been consistently found in a proportion of patients, and it is known that specific 5-HT transporter gene (SLC6A4) variants modulate transporter reuptake function, therefore possibly influencing the occurrence of hyperserotonemia in a subset of...

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PMID: 15094787
DOI: 10.1038/sj.mp.4001409

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HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variants of the serotonin transporter gene (SLC6A4) significantly contribute to hyperserotonemia in autism.PMID 15094787Read ↗

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