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Article

Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors.

American journal of human genetics - 1 Aug 2005

Sutcliffe James S, Delahanty Ryan J, Prasad Harish C, McCauley Jacob L, Han Qiao, Jiang Lan, Li Chun, Folstein Susan E, Blakely Randy D

Abstract excerpt

Autism is a spectrum of neurodevelopmental disorders with a primarily genetic etiology exhibiting deficits in (1) development of language and (2) social relationships and (3) patterns of repetitive, restricted behaviors or interests and resistance to change. Elevated platelet serotonin (5-HT) in 20%-25% of cases and efficacy of selective 5-HT reuptake inhibitors (SSRIs) in treating anxiety, depression, and...

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Identifiers

PMID: 15995945
DOI: 10.1086/432648
PMCID: PMC1224529

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HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors.PMID 15995945Read ↗

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