Article
5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder.
Psychiatry research - 15 Aug 2010
Hranilovic Dubravka, Blazevic Sofia, Babic Marina, Smurinic Maja, Bujas-Petkovic Zorana, Jernej Branimir
Abstract excerpt
Disturbances in the expression/function of the 5-HT2A receptor are implicated in autism. The association of the 5-HT2A receptor gene with autism was studied in the Croatian population. Distribution frequencies for alleles, genotypes and haplotypes of -1438 A/G and His452Tyr polymorphisms were compared in samples of 103 autistic and 214 control subjects. Significant overrepresentation of the G allele and the GG...
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