Article
Genetic variation in miR-100 rs1834306 is associated with decreased risk for esophageal squamous cell carcinoma in Kazakh patients in northwest China.
International journal of clinical and experimental pathology - 1 Jan 2015
Zhu Jianbo, Yang Lan, You Weiyan, Cui Xiaobin, Chen Yunzhao, Hu Jianming, Liu Wei, Li Shugang, Song Xiaoyue, Wei Yutao, Zhang Wenjie, Li Feng
Abstract excerpt
MicroRNAs (miRNAs) are a family of small noncoding RNAs that act as oncogenes and tumor suppressors. Single nucleotide polymorphisms (SNPs) in miRNAs may be associated with changes in phenotype and function. The aim of this study was to verify whether genetic variations in candidate microRNA (miRNA or miR) genes could contribute to esophageal squamous cell carcinoma (ESCC) susceptibility. A case-control study in...
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