Article
A genetic variant in microRNA-196a2 is associated with increased cancer risk: a meta-analysis.
Molecular biology reports - 1 Jan 2012
Wang Feng, Ma Yan-Lei, Zhang Peng, Yang Jian-Jun, Chen Hong-Qi, Liu Zhi-Hua, Peng Jia-Yuan, Zhou Yu-Kun, Qin Huan-Long
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNA molecules that function as negative regulators of gene expression. Common genetic variants (single nucleotide polymorphisms, SNPs) in miRNA genes may alter their expression or maturation resulting in varied functional consequences. Until now, several studies had evaluated the association between the polymorphisms in the hsa-miR-196a2 rs11614913 and cancer risk in...
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