Article
miR-449b rs10061133 and miR-4293 rs12220909 polymorphisms are associated with decreased esophageal squamous cell carcinoma in a Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Nov 2015
Zhang Ping, Wang Jianguo, Lu Ting, Wang Xiaofeng, Zheng Yabiao, Guo Shicheng, Yang Yajun, Wang Mengyun, Kolluri Vijay Kumar, Qiu Lixin, Shen Fangyuan, Fan Lixia, Li Jin, Wang Yanong, Wei Qingyi, Jin Li, Wang Jiucun, Wang Minghua
Abstract excerpt
Esophageal cancer is one of the most aggressive cancers in the world, 70% of which are from China and esophageal squamous cell carcinoma (ESCC) is the major histopathological form (>90%). The single nucleotide polymorphisms (SNPs) in mature sequence of microRNA (miRNA) (mmSNPs) could cause the alteration of microRNA expression and contribute to the susceptibility of cancers. To evaluate the association between...
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