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Article

A Genetic Variant in miR-124 Decreased the Susceptibility to Esophageal Squamous Cell Carcinoma in a Chinese Kazakh Population.

Genetic testing and molecular biomarkers - 1 Jan 2018

Wu Fei, Li Mei, You Weiyan, Ji Yu, Cui Xiaobin, Hu Jianming, Chen Yunzhao, Pang Lijuan, Li Shugang, Wei Yutao, Yang Lan, Li Feng

Abstract excerpt

AIMS: Esophageal squamous cell carcinoma (ESCC) is characterized by high prevalence and mortality worldwide, and it is very highly prevalent in China. ESCC is caused by various factors, including microRNAs (miRNAs) whose expression have been shown to play a major role in tumor generation. Single nucleotide polymorphisms (SNPs) in miRNAs could affect susceptibility to numerous cancers. This study aimed to evaluate...

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PMID: 29227754
DOI: 10.1089/gtmb.2017.0115

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