Article
A Genetic Variant in miRNA-219-1 Is Associated with Risk of Esophageal Squamous Cell Carcinoma in Chinese Kazakhs.
Disease markers - 1 Jan 2015
Song Xiaoyue, You Weiyan, Zhu Jianbo, Cui Xiaobin, Hu Jianming, Chen Yunzhao, Liu Wei, Wang Lianghai, Li Shugang, Wei Yutao, Yang Lan, Li Feng
Abstract excerpt
BACKGROUND: Esophageal cancer (EC), an aggressive digestive tract malignancy, is one of the leading causes of cancer-related deaths worldwide. Besides environmental risk factors, genetic factors might play a key role in the EC carcinogenesis. The aim of the study is to evaluate the association of miR219-1 single-nucleotide polymorphisms (SNPs) with EC. METHODS: A total of 248 Kazakh esophageal squamous cell...
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