Article
Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk.
Cancer prevention research (Philadelphia, Pa.) - 1 Nov 2008
Ye Yuanqing, Wang Kenneth K, Gu Jian, Yang Hushan, Lin Jie, Ajani Jaffer A, Wu Xifeng
Abstract excerpt
MicroRNAs (miRNA) can act as oncogenes or tumor suppressors and modulate the expression of approximately one third of all human genes. To test the hypothesis that adverse alleles in miRNA-related genes may increase the risk for esophageal cancer, we assessed the associations between esophageal ca...
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