Article
Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay.
Experimental and molecular pathology - 1 Oct 2015
Arnold Alexander, Bahra Marcus, Lenze Dido, Bradtmöller Maren, Guse Katrin, Gehlhaar Claire, Bläker Hendrik, Heppner Frank L, Koch Arend
Abstract excerpt
In order to study molecular similarities and differences of intrahepatic (IH-CCA) and extrahepatic (EH-CCA) cholangiocarcinoma, 24 FFPE tumor samples (13 IH-CCA, 11 EH-CCA) were analyzed for whole genome copy number variations (CNVs) using a new high-density Molecular Inversion Probe Single Nucleotide Polymorphism (MIP SNP) assay. Common in both tumor subtypes the most frequent losses were detected on chromosome...
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