Article
Patterns of chromosomal copy-number alterations in intrahepatic cholangiocarcinoma.
BMC cancer - 14 Mar 2015
Dalmasso Cyril, Carpentier Wassila, Guettier Catherine, Camilleri-Broët Sophie, Borelli Wyllians Vendramini, Campos Dos Santos Cedália Rosane, Castaing Denis, Duclos-Vallée Jean-Charles, Broët Philippe
Abstract excerpt
BACKGROUND: Intrahepatic cholangiocarcinomas (ICC) are relatively rare malignant tumors associated with a poor prognosis. Recent studies using genome-wide sequencing technologies have mainly focused on identifying new driver mutations. There is nevertheless a need to investigate the spectrum of copy number aberrations in order to identify potential target genes in the altered chromosomal regions. The aim of this...
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