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Article

CREB3L4, INTS3, and SNAPAP are targets for the 1q21 amplicon frequently detected in hepatocellular carcinoma.

Cancer genetics and cytogenetics - 1 Jan 2008

Inagaki Yoshikazu, Yasui Kohichiroh, Endo Mio, Nakajima Tomoaki, Zen Keika, Tsuji Kazuhiro, Minami Masahito, Tanaka Shinji, Taniwaki Masafumi, Itoh Yoshito, Arii Shigeki, Okanoue Takeshi

Abstract excerpt

High-density single nucleotide polymorphism (SNP) array analysis revealed novel amplification at 1q21 in cell lines derived from hepatocellular carcinomas (HCCs). Fluorescence in situ hybridization and real-time quantitative polymerase chain reaction studies verified amplification at 1q21. An increase in copy number at the region was detected in 32 of the 36 primary HCC tumors (89%). To identify the targets for...

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Identifiers

PMID: 18068530
DOI: 10.1016/j.cancergencyto.2007.09.013

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INTS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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