Article
Mutations of candidate tumor suppressor genes at chromosome 3p in intrahepatic cholangiocarcinoma.
Experimental and molecular pathology - 1 Dec 2017
You Huey-Ling, Huang Wan-Ting, Liu Ting-Ting, Weng Shao-Wen, Eng Hock-Liew
Abstract excerpt
The genetic status of candidate tumor suppressor genes (TSGs) at chromosome 3p has not yet been elucidated in intrahepatic cholangiocarcinoma (iCCA). Herein, we retrospectively investigated 32 fresh iCCA case samples from a single medical institution to clarify mutations of 11 TSGs by next-generation sequencing. Validation of the mutations was performed on the MassARRAY platform or by high-resolution melting...
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