Article
Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease.
Human molecular genetics - 15 Dec 2009
Kishnani Priya S, Chuang Tzu-Po, Bali Deeksha, Koeberl Dwight, Austin Stephanie, Weinstein David A, Murphy Elaine, Chen Ying-Ting, Boyette Keri, Liu Chu-Hao, Chen Yuan-Tsong, Li Ling-Hui
Abstract excerpt
Hepatocellular adenoma (HCA) is a frequent long-term complication of glycogen storage disease type I (GSD I) and malignant transformation to hepatocellular carcinoma (HCC) is known to occur in some cases. However, the molecular pathogenesis of tumor development in GSD I is unclear. This study was conducted to systematically investigate chromosomal and genetic alterations in HCA associated with GSD I. Genome-wide...
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