Article
Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer.
Cancer science - 1 May 2010
Tada Motohisa, Kanai Fumihiko, Tanaka Yasuo, Sanada Masashi, Nannya Yasuhito, Tateishi Keisuke, Ohta Miki, Asaoka Yoshinari, Seto Motoko, Imazeki Fumio, Yoshida Haruhiko, Ogawa Seishi, Yokosuka Osamu, Omata Masao
Abstract excerpt
We sought to identify genomic changes that could be useful for clinical application, focusing on chromosomal instability and using a high-density single nucleotide polymorphism (SNP) array. We analyzed 34 gastric cancer cell lines for areas of DNA that exhibited copy number changes using the Affymetrix GeneChip Human Mapping 50 K Arrays. The results obtained with the cell lines were verified in 42 gastric cancer...
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