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Article

Frequent amplification of CENPF, GMNN and CDK13 genes in hepatocellular carcinomas.

PloS one - 1 Jan 2012

Kim Hye-Eun, Kim Dae-Ghon, Lee Kyung Jin, Son Jang Geun, Song Min-Young, Park Young-Mi, Kim Jae-Jung, Cho Sung-Won, Chi Sung-Gil, Cheong Hyun Sub, Shin Hyoung Doo, Lee Sang-Wook, Lee Jong-Keuk

Abstract excerpt

Genomic changes frequently occur in cancer cells during tumorigenesis from normal cells. Using the Illumina Human NS-12 single-nucleotide polymorphism (SNP) chip to screen for gene copy number changes in primary hepatocellular carcinomas (HCCs), we initially detected amplification of 35 genes from four genomic regions (1q21-41, 6p21.2-24.1, 7p13 and 8q13-23). By integrated screening of these genes for both DNA...

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Source

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Identifiers

PMID: 22912832
DOI: 10.1371/journal.pone.0043223
PMCID: PMC3418236

Genes

CDK13
CENPF
GMNN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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