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Article

Inferring the Origin of Metastases from Cancer Phylogenies.

Cancer research - 1 Oct 2015

Hong Woo Suk, Shpak Max, Townsend Jeffrey P

Abstract excerpt

Determining the evolutionary history of metastases is a key problem in cancer biology. Several recent studies have presented inferences regarding the origin of metastases based on phylogenies of cancer lineages. Many of these studies have concluded that the observed monophyly of metastatic subclones favored metastasis-to-metastasis spread ("a metastatic cascade" rather than parallel metastases from the primary...

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Identifiers

PMID: 26260528
DOI: 10.1158/0008-5472.CAN-15-1889
PMCID: PMC4833389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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