Article
Tracing the origins of metastasis.
The Journal of pathology - 1 Jan 2011
Nguyen Don X
Abstract excerpt
Cancer metastasis is often considered an orderly sequence of events leading to the colonization of distal organs by malignant cells. In fact, the evolution of metastatic disease is a dynamic process that is influenced by unique cellular lineages, altered microenvironments, distinct anatomical restrictions and multiple genetic and epigenetic alterations. These factors all contribute to variable clinical courses,...
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