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Article

Origins of metastatic traits.

Cancer cell - 14 Oct 2013

Vanharanta Sakari, Massagué Joan

Abstract excerpt

How cancer cells acquire the competence to colonize distant organs remains a central question in cancer biology. Tumors can release large numbers of cancer cells into the circulation, but only a small proportion of these cells survive on infiltrating distant organs and even fewer form clinically meaningful metastases. During the past decade, many predictive gene signatures and specific mediators of metastasis...

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Identifiers

PMID: 24135279
DOI: 10.1016/j.ccr.2013.09.007
PMCID: PMC3998120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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