Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation in PARK10 is not associated with risk and age at onset of Parkinson's disease in large clinical cohorts.

Neurobiology of aging - 1 Oct 2015

Simón-Sánchez Javier, Heutink Peter, Gasser Thomas

Abstract excerpt

A recent study in autopsy-confirmed Parkinson's disease (PD) patients and controls revived the debate about the role of PARK10 in this disorder. In an attempt to replicate these results and further understand the role of this locus in the risk and age at onset of PD, we decided to explore NeuroX genotyping and whole exome sequencing data from 2 large independent cohorts of clinical patients and controls from the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Cohort Studies
Share to Exome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genotyping Techniques

Share to Parkinson Disease

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 26260214
DOI: 10.1016/j.neurobiolaging.2015.07.008
PMCID: PMC8978882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in PARK10 is not associated with risk and age at onset of Parkinson's disease in large clinical cohorts.PMID 26260214Read ↗

Association mapping of the PARK10 region for Parkinson's disease susceptibility genes.Semantic proximity Read ↗

Fine-mapping and candidate gene investigation within the PARK10 locus.Semantic proximity Read ↗

Lack of evidence for association of Parkin promoter polymorphism (PRKN-258) with increased risk of Parkinson's disease.Semantic proximity Read ↗

Lack of evidence for genetic association of saposins A, B, C and D with Parkinson diseaseSemantic proximity Read ↗

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.Semantic proximity Read ↗

Genetic risk and age in Parkinson's disease: Continuum not stratum.Semantic proximity Read ↗

Parkinson disease age of onset GWAS: defining heritability, genetic loci and a-synuclein mechanismsSemantic proximity Read ↗

No evidence of association between PGK1 variants and Parkinsons diseaseSemantic proximity Read ↗

Parkinson's disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanismsSemantic proximity Read ↗

Association study of Parkin gene polymorphisms with idiopathic Parkinson disease.Semantic proximity Read ↗

Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease: Evidence From the COURAGE-PD Consortium.Semantic proximity Read ↗

The gene responsible for PARK6 Parkinson's disease, PINK1, does not influence common forms of parkinsonism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.