Article
Association mapping of the PARK10 region for Parkinson's disease susceptibility genes.
Parkinsonism & related disorders - 1 Jan 2014
Wan Jia Y, Edwards Karen L, Hutter Carolyn M, Mata Ignacio F, Samii Ali, Roberts John W, Agarwal Pinky, Checkoway Harvey, Farin Federico M, Yearout Dora, Zabetian Cyrus P
Abstract excerpt
BACKGROUND: Previous studies indicate that as many as six genes within the PARK10 region (RNF11, UQCRH, HIVEP3, EIF2B3, USP24, ELAVL4) might modify susceptibility or age at onset in Parkinson's disease (PD). METHODS: We sought to identify new PD susceptibility genes and to validate previously nominated candidate genes within the PARK10 region using a two-stage design. We used data from a large, publicly-available...
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