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Article

Formation and characterisation of neuromuscular junctions between hiPSC derived motoneurons and myotubes

26 Jul 2015

Abstract excerpt

Striated skeletal muscle cells from humans represent a valuable source for in vitro studies of the motoric system as well as for pathophysiological investigations in the clinical settings. Myoblasts can readily be grown from human muscle tissue. However, if muscle tissue is unavailable, myogenic cells can be generated from human induced pluripotent stem cells (hiPSCs) preferably without genetic engineering. Our...

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PMID: 26255853
DOI: 10.1016/j.scr.2015.07.005

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