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Skeletal muscle differentiation of human iPSCs meets bioengineering strategies: perspectives and challenges

7 Apr 2022

Abstract excerpt

Although skeletal muscle repairs itself following small injuries, genetic diseases or severe damages may hamper its ability to do so. Induced pluripotent stem cells (iPSCs) can generate myogenic progenitors, but their use in combination with bioengineering strategies to modulate their phenotype has not been sufficiently investigated. This review highlights the potential of this combination aimed at pushing the...

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PMID: 35393412
DOI: 10.1038/s41536-022-00216-9

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