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Article

Molecular genetic response of Xiphophorus maculatus-X. couchianus interspecies hybrid skin to UVB exposure.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Dec 2015

Lu Yuan, Bowswell Mikki, Bowswell William, Yang Kuan, Schartl Manfred, Walter Ronald B

Abstract excerpt

The phenotypic and genetic similarities between Xiphophorus and human melanoma render Xiphophorus a useful animal model for studying the genetic basis of melanoma etiology. In the Xiphophorus model, melanoma has been shown to be inducible by ultraviolet light (UVB) exposure among interspecies hybrids, but not in parental line fish similarly treated. This leads to questions of what genes are responsive to UVB...

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Identifiers

PMID: 26254713
DOI: 10.1016/j.cbpc.2015.07.011
PMCID: PMC4662913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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